When priming a line for albumin it is inevitable that the dang stuff never wants to flow.
It just sits in the bottle refusing to come out
even though you have opened the vent
pierced the vent with a large bore needle.
I have learned a trick,
it's so simple you won't believe me.
When hanging albumin just let the bottle hang for several minutes.
Gather your tubing and such and just let your albumin sit there and chill.
Then spike your bottle in one quick motion and pop the vent.
If you do this I promise you will never have a problem priming a line with albumin again.